1 Senn L, Vuichard D, Widmer A, Zanetti G, Kuster S. Mise à jour des recommandations d’antibioprophylaxie chirurgicale en Suisse, 2015. Bulletin SwissNoso. 2015;20(1):1–8.
2 Senn L, Vuichard D, Widmer A, Zanetti G, Kuster S. Sample-Guideline: perioperative Antibiotikaprophylaxe. SwissNoso Bulletin. 2018; online only.
3 Shah RP, Lauthen D, Geller JA, Cooper HJ. Average Operative Times for 1,313 Primary Total Hip Arthroplasty and 1,300 Primary Total Knee Arthroplasty Over 39 Months Are Roughly Equal to Medicare Attributed Operative Times. J Arthroplasty. 2019;34(8):1553–6.
4 Gianakos AL, Hurley ET, Haring RS, Yoon RS, Liporace FA. Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty: A Meta-Analysis. JBJS Rev. 2018; 6(5): e1.
5 Muller D, Kaiser D, Sairanen K, Studhalter T, Uckay I. Antimicrobial Prophylaxis for the Prevention of Surgical Site Infections in Orthopaedic Oncology – A Narrative Review of Current Concepts. J Bone Jt Infect. 2019;4(6):254–63.
6 Davat M, Wuarin L, Stafylakis D, et al. Should antibiotic prophylaxis before orthopedic implant surgery depend on the duration of pre-surgical hospital stay? Antimicrob Resist Infect Control. 2018;7:131.
7 Parvizi J, Gehrke T, Chen AF. Proceedings of the International Consensus on Periprosthetic Joint Infection. Bone Joint J. 2013;95-B(11):1450–2.
8 Pai MP, Bearden DT. Antimicrobial dosing considerations in obese adult patients. Pharmacotherapy. 2007;27(8):1081–91.
9 Koopman E, Nix DE, Erstad BL, et al. End-of-procedure cefazolin concentrations after administration for prevention of surgical-site infection. Am J Health Syst Pharm. 2007;64(18):1927–34.
10 Morris AJ, Roberts SA, Grae N, Frampton CM. Surgical site infection rate is higher following hip and knee arthroplasty when cefazolin is underdosed. Am J Health Syst Pharm. 2020;77(6):434–40.
11 Meng L, Mui E, Holubar MK, Deresinski SC. Comprehensive Guidance for Antibiotic Dosing in Obese Adults. Pharmacotherapy. 2017; 37(11):1415–31.
12 Lübbeke A, Zingg M, Vu D, et al. Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty. Acta Orthop. 2016;87(2):132–8.
13 Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm .2013;70(3):195–283.
14 Aboltins CA, Tan TL, Townsend R, Turner D. QUESTION 2: What are the appropriate weight-adjusted prophylactic antibiotic dosages? International Consensus Meeting in Philadelphia. 2018; Sectio 1 - Part II:294–5.
15 Barbour A, Schmidt S, Rout WR, Ben-David K, Burkhardt O, Derendorf H. Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery. Int J Antimicrob Agents. 2009;34(3):231–5.
16 Hasler A, Unterfrauner I, Olthof MGL, et al. Deep surgical site infections following double-dose perioperative antibiotic prophylaxis in adult obese orthopedic patients. Int J Infect Dis. 2021;108:537–42.
17 Lanoiselée J, Chaux R, Hodin S, et al. Population pharmacokinetic model of cefazolin in total hip arthroplasty. Sci Rep. 2021;11(1):19763.
18 Junker T, Mujagic E, Hoffmann H, et al. Prevention and control of surgical site infections: review of the Basel Cohort Study. Swiss Med Wkly. 2012;142:w13616.
19 Weber WP, Mujagic E, Zwahlen M, et al. Timing of surgical antimicrobial prophylaxis: a phase 3 randomised controlled trial. Lancet Infect Dis. 2017;17(6):605–14.
20 Ho VP, Nicolau DP, Dakin GF, et al. Cefazolin dosing for surgical prophylaxis in morbidly obese patients. Surg Infect (Larchmt). 2012;13(1):33–7.
21 Lingard L, Regehr G, Cartmill C, et al. Evaluation of a preoperative team briefing: a new communication routine results in improved clinical practice. BMJ Qual Saf. 2011;20(6):475–82.
22 de Vries EN, Dijkstra L, Smorenburg SM, Meijer RP, Boermeester MA. The SURgical PAtient Safety System (SURPASS) checklist optimizes timing of antibiotic prophylaxis. Patient Saf Surg. 2010;4(1):6.
23 Haney V, Maman S, Prozesky J, Bezinover D, Karamchandani K. Improving intraoperative administration of surgical antimicrobial prophylaxis: a quality improvement report. BMJ Open Qual. 2020;9(3).
24 Castells M, Khan DA, Phillips EJ. Penicillin Allergy. N Engl J Med. 2019;381(24):2338–51.
25 Macy E, Ngor EW. Safely diagnosing clinically significant penicillin allergy using only penicilloyl-poly-lysine, penicillin, and oral amoxicillin. J Allergy Clin Immunol Pract. 2013;1(3):258–63.
26 Trubiano JA, Stone CA, Grayson ML, et al. The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration. J Allergy Clin Immunol Pract. 2017;5(6):1532–42.
27 Shenoy ES, Macy E, Rowe T, Blumenthal KG. Evaluation and Management of Penicillin Allergy: A Review. Jama. 2019;321(2):188–99.
28 Jörg L, Fricker M, Helbling A. Allergie à la pénicilline. Forum Med Suisse. 2017;17(10):236–40.
29 Klinik für Infektiologie und Spitalhygiene, in Zusammenarbeit mit PD Dr. Schmid-Grendelmeier, Universitätsspital Zürich. Vorgehen bei Verdacht auf Penicillin- resp. Beta-Lactamallergie. Available at: https://www.usz.ch/fachbereich/infektiologie/ueber-uns/spitalhygiene/.
30 Wyles CC, Hevesi M, Osmon DR, et al. 2019 John Charnley Award: Increased risk of prosthetic joint infection following primary total knee and hip arthroplasty with the use of alternative antibiotics to cefazolin: the value of allergy testing for antibiotic prophylaxis. Bone Joint J. 2019;101-b(6_Supple_B):9–15.
31 Hill C, Flamant R, Mazas F, Evrard J. Prophylactic cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomised trial. Lancet. 1981;1(8224):795–6.
32 Siddiqi A, Forte SA, Docter S, Bryant D, Sheth NP, Chen AF. Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty: A Systematic Review and Meta-Analysis. J Bone Joint Surg Am. 2019;101(9):828–42.
33 Bryson DJ, Morris DL, Shivji FS, Rollins KR, Snape S, Ollivere BJ. Antibiotic prophylaxis in orthopaedic surgery: difficult decisions in an era of evolving antibiotic resistance. Bone Joint J. 2016;98-b(8):1014–9.
34 de Jonge SW, Boldingh QJJ, Solomkin JS, et al. Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis. Lancet Infect Dis. 2020;20(10):1182–92.
35 McDonald M, Grabsch E, Marshall C, Forbes A. Single- versus multiple-dose antimicrobial prophylaxis for major surgery: a systematic review. Aust N Z J Surg. 1998;68(6):388–96.
36 Wall R, Klenerman L, McCullough C, Fyfe I. A comparison of teicoplanin and cefuroxime as prophylaxis for orthopaedic implant surgery: a preliminary report. J Antimicrob Chemother. 1988; 21 Suppl A:141–6.
37 Periti P, Stringa G, Mini E. Comparative multicenter trial of teicoplanin versus cefazolin for antimicrobial prophylaxis in prosthetic joint implant surgery. Italian Study Group for Antimicrobial Prophylaxis in Orthopedic Surgery. Eur J Clin Microbiol Infect Dis. 1999;18(2):113–9.
38 Mollan RA, Haddock M, Webb CH. Teicoplanin vs cephamandole for antimicrobial prophylaxis in prosthetic joint implant surgery: (preliminary results). Eur J Surg Suppl. 1992;(567):19–21.
39 Garotta F, Pamparana F. Antimicrobial prophylaxis with ceftizoxime versus cefuroxime in orthopedic surgery. Ceftizoxime Orthopedic Surgery Italian Study Group. J Chemother. 1991;3 Suppl 2:34–5.
40 Gatell JM, Garcia S, Lozano L, Soriano E, Ramon R, SanMiguel JG. Perioperative cefamandole prophylaxis against infections. J Bone Joint Surg Am. 1987;69(8):1189–93.
41 Shahi A, Parvizi J. Prevention of Periprosthetic Joint Infection. Arch Bone Jt Surg .2015;3(2):72–81.
42 Panula VJ, Alakylä KJ, Venäläinen MS, et al. Risk factors for prosthetic joint infections following total hip arthroplasty based on 33,337 hips in the Finnish Arthroplasty Register from 2014 to 2018. Acta Orthop. 2021:1–8.
43 Wymenga AB, Hekster YA, Theeuwes A, Muytjens HL, van Horn JR, Slooff TJ. Antibiotic use after cefuroxime prophylaxis in hip and knee joint replacement. Clin Pharmacol Ther. 1991;50(2):215–20.
44 Wymenga A, van Horn J, Theeuwes A, Muytjens H, Slooff T. Cefuroxime for prevention of postoperative coxitis. One versus three doses tested in a randomized multicenter study of 2,651 arthroplasties. Acta Orthop Scand. 1992;63(1):19–24.
45 Engesaeter LB, Lie SA, Espehaug B, Furnes O, Vollset SE, Havelin LI. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand. 2003;74(6):644–51.
46 Helsedirektoratet. Antibiotika i sykehus, KAPITTEL 1.8 1.8. Ortopedisk kirurgi, Ortopedisk kirurgi med leddproteser. Available at: https://www.helsedirektoratet.no/retningslinjer/antibiotika-i-sykehus/antibiotikaprofylakse-ved-kirurgi/ortopedisk-kirurgi. Accessed November 5.
47 Tan TL, Shohat N, Rondon AJ, et al. Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty: A Single Dose Is as Effective as Multiple Doses. J Bone Joint Surg Am. 2019; 101(5):429–37.
48 ANQ, SWISSNOSO. Nationaler Vergleichsbericht Programm zur Überwachung postoperativer Wundinfektionen. Swissnoso. Available at: https://www.swissnoso.ch/fileadmin/module/ssi_surveillance/Dokumente_D/9_Resultate/20200925_ANQakut_Wundinfektionen_Nationaler-Vergleichsbericht_2018-19_V1.1.pdf. Accessed November 5.
49 Osmon DR, Berbari EF, Berendt AR, et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2013;56(1):e1–e25.
50 Parvizi J, Tan TL, Goswami K, et al. The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria. J Arthroplasty. 2018;33(5):1309-14.e2.
51 McNally M, Sousa R, Wouthuyzen-Bakker M, et al. The EBJIS definition of periprosthetic joint infection. Bone Joint J. 2021;103-b(1):18–25.
52 Harbarth S, Samore MH, Lichtenberg D, Carmeli Y. Prolonged antibiotic prophylaxis after cardiovascular surgery and its effect on surgical site infections and antimicrobial resistance. Circulation. 2000;101(25):2916–21.
53 Branch-Elliman W, O’Brien W, Strymish J, Itani K, Wyatt C, Gupta K. Association of Duration and Type of Surgical Prophylaxis With Antimicrobial-Associated Adverse Events. JAMA Surg. 2019;154(7):590–8.
54 Anderson PA, Bernatz J, Safdar N. Clostridium difficile Infection: An Orthopaedic Surgeon’s Guide to Epidemiology, Management, and Prevention. J Am Acad Orthop Surg. 2017;25(3):214–23.
55 Oppelaar MC, Zijtveld C, Kuipers S, et al. Evaluation of Prolonged vs Short Courses of Antibiotic Prophylaxis Following Ear, Nose, Throat, and Oral and Maxillofacial Surgery: A Systematic Review and Meta-analysis. JAMA Otolaryngol Head Neck Surg. 2019;145(7):610–6.
56 Tan TL, Huang W, Seyler TM. Is one dose of preoperative antibiotic adequate for patients undergoing total joint arthroplasty (TJA)? Available at: https://icmphilly.com/questions/is-one-dose-of-preoperative-antibiotic-adequate-for-patients-undergoing-total-joint-arthroplasty-tja/. Accessed November 5.
57 Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. 2017;152(8):784–91.
58 Yates AJ, Jr. Postoperative prophylactic antibiotics in total joint arthroplasty. Arthroplast Today. 2018;4(1):130–1.
59 Bornet M-A, Beaud F, Bardy D, Boulat O, Kissling S. Dosage de la cystatine C dans l’évaluation de la fonction rénale. Forum Med Suisse. 2019;19(2324):391–3.
60 Heydemann JS, Nelson CL. Short-term preventive antibiotics. Clin Orthop Relat Res. 1986;(205):184–7.
61 Tang WM, Chiu KY, Ng TP, Yau WP, Ching PT, Seto WH. Efficacy of a single dose of cefazolin as a prophylactic antibiotic in primary arthroplasty. J Arthroplasty. 2003;18(6):714–8.
62 van Kasteren ME, Manniën J, Ott A, Kullberg BJ, de Boer AS, Gyssens IC. Antibiotic prophylaxis and the risk of surgical site infections following total hip arthroplasty: timely administration is the most important factor. Clin Infect Dis. 2007;44(7):921–7.
63 Parvizi J, Zmistowski B, Berbari EF, et al. New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society. Clin Orthop Relat Res. 2011;469(11):2992–4.